R-87366
Product Specifications
UNSPSC Description
R-87366 is a water-soluble human immunodeficiency virus (HIV) protease inhibitor. R-87366 has potent inhibitory for HIV protease with a Ki value of 11 nM. R-87366 can be used for the research of anti-human immunodeficiency virus (HIV)[1].
Target Antigen
HIV Protease
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-87366.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CCC1)[C@@H]1C(NC(C)(C)C)=O)[C@@H](O)[C@@H](NC([C@H](CC(N)=O)NC(C2=CN=C3C(C=CC=C3)=N2)=O)=O)CC4=CC=CC=C4
Molecular Weight
617.70
References & Citations
[1]T Komai, et al. In vitro and ex vivo anti-human immunodeficiency virus (HIV) activities of a new water-soluble HIV protease inhibitor, R-87366, containing (2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid. Biol Pharm Bull. 1997 Feb;20(2):175-80.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19232/R-87366-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19232/
Clinical Information
Phase 2
CAS Number
144779-91-9
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