R-87366

R-87366 is a water-soluble human immunodeficiency virus (HIV) protease inhibitor. R-87366 has potent inhibitory for HIV protease with a Ki value of 11 nM. R-87366 can be used for the research of anti-human immunodeficiency virus (HIV) [1].

Product Specifications

CAS Number

[144779-91-9]

UNSPSC

12352005

Target

HIV Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/r-87366.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CCC1)[C@@H]1C(NC(C)(C)C)=O)[C@@H](O)[C@@H](NC([C@H](CC(N)=O)NC(C2=CN=C3C(C=CC=C3)=N2)=O)=O)CC4=CC=CC=C4

Molecular Formula

C32H39N7O6

Molecular Weight

617.70

References & Citations

[1]T Komai, et al. In vitro and ex vivo anti-human immunodeficiency virus (HIV) activities of a new water-soluble HIV protease inhibitor, R-87366, containing (2S,3S) -3-amino-2-hydroxy-4-phenylbutanoic acid. Biol Pharm Bull. 1997 Feb;20 (2) :175-80.