Ensaculin (free base)
Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors. Ensaculin free base is a memory-enhancing agent. Ensaculin free base has the potential as an antidementia agent acting on various transmitter systems[1].
Product Specifications
CAS Number
[155773-59-4]
Product Name Alternative
KA-672; Anseculin
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; iGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ensaculin-free-base.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C(C)=C1C)C=C(OCCCN3CCN(CC3)C4=C(OC)C=CC=C4)C(OC)=C2
Molecular Formula
C26H32N2O5
Molecular Weight
452.54
References & Citations
[1]Hoerr R, Noeldner M. Ensaculin (KA-672 HCl) : a multitransmitter approach to dementia treatment. CNS Drug Rev. 2002 Summer;8 (2) :143-58.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor;5-HT7 Receptor
Available Sizes
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