(E/Z) -Rigosertib (sodium)

Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Product Specifications

CAS Number

[1225497-78-8]

Product Name Alternative

(E/Z) -ON-01910 (sodium)

UNSPSC

12352200

Hazard Statement

H302-H315-H319-H335

Target

Polo-like Kinase (PLK)

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/e-z-rigosertib-sodium.html

Solubility

10 mM in DMSO

Smiles

O=C(CNC1=CC(CS(=O)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O)=CC=C1OC)O[Na]

Molecular Formula

C21H24NNaO8S

Molecular Weight

473.47

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Gumireddy K, et al. ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell. 2005 Mar;7 (3) :275-86.

Shipping Conditions

Room temperature

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Isoform

PLK1

Available Sizes

Curated Selection

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