(E/Z) -Rigosertib (sodium)
Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Product Specifications
CAS Number
[1225497-78-8]
Product Name Alternative
(E/Z) -ON-01910 (sodium)
UNSPSC
12352200
Hazard Statement
H302-H315-H319-H335
Target
Polo-like Kinase (PLK)
Type
Biochemical Assay Reagents
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/e-z-rigosertib-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C(CNC1=CC(CS(=O)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O)=CC=C1OC)O[Na]
Molecular Formula
C21H24NNaO8S
Molecular Weight
473.47
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Gumireddy K, et al. ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell. 2005 Mar;7 (3) :275-86.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
PLK1
Available Sizes
Curated Selection
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