DAGLβ-IN-1
DAGLβ-IN-1 is an inhibitor of diacylglycerol lipase-β (DAGLβ), serves as a versatile intermediate for the design of DAGL-tailored activity-based probes[1][2].
Product Specifications
CAS Number
1402612-61-6
UNSPSC
12352005
Target
DAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/daglβ-in-1.html
Purity
98.22
Solubility
10 mM in DMSO
Smiles
O=C(N1N=NC(C2=CC=C(OC(F)(F)F)C=C2)=C1)N(CCC3=CC=CC=C3)CCCCCNC(OC(C)(C)C)=O
Molecular Formula
C28H34F3N5O4
Molecular Weight
561.60
References & Citations
[1]Ku-Lung Hsu, et al. Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis. J Med Chem . 2013 Nov 14;56 (21) :8257-69.|[2]Tiziana Bisogno, et al. Cloning of the First sn1-DAG Lipases Points to the Spatial and Temporal Regulation of Endocannabinoid Signaling in the Brain. J Cell Biol. 2003 Nov 10;163 (3) :463-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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