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DAGLβ-IN-1

DAGLβ-IN-1 is an inhibitor of diacylglycerol lipase-β (DAGLβ), serves as a versatile intermediate for the design of DAGL-tailored activity-based probes[1][2].

Product Specifications

CAS Number

1402612-61-6

UNSPSC

12352005

Target

DAGL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/daglβ-in-1.html

Purity

98.22

Solubility

10 mM in DMSO

Smiles

O=C(N1N=NC(C2=CC=C(OC(F)(F)F)C=C2)=C1)N(CCC3=CC=CC=C3)CCCCCNC(OC(C)(C)C)=O

Molecular Formula

C28H34F3N5O4

Molecular Weight

561.60

References & Citations

[1]Ku-Lung Hsu, et al. Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis. J Med Chem . 2013 Nov 14;56 (21) :8257-69.|[2]Tiziana Bisogno, et al. Cloning of the First sn1-DAG Lipases Points to the Spatial and Temporal Regulation of Endocannabinoid Signaling in the Brain. J Cell Biol. 2003 Nov 10;163 (3) :463-8.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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