IRE1α kinase-IN-7
IRE1α kinase-IN-7 (compound 4) is an IRE1α kinase inhibitor. IRE1α kinase-IN-7 can be used for research of endoplasmic reticulum stress-related diseases[1].
Product Specifications
CAS Number
1414938-22-9
UNSPSC
12352005
Target
IRE1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ire1α-kinase-in-7.html
Solubility
10 mM in DMSO
Smiles
CC(C)C1=NC(C2=CC=C(NC(NC3=CC=CC(C(F)(F)F)=C3)=O)C4=C2C=CC=C4)=C5N1C=CN=C5NC
Molecular Formula
C28H25F3N6O
Molecular Weight
518.53
References & Citations
[1]Wang L, et al. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012 Dec;8 (12) :982-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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