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IRE1α kinase-IN-7

IRE1α kinase-IN-7 (compound 4) is an IRE1α kinase inhibitor. IRE1α kinase-IN-7 can be used for research of endoplasmic reticulum stress-related diseases[1].

Product Specifications

CAS Number

1414938-22-9

UNSPSC

12352005

Target

IRE1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ire1α-kinase-in-7.html

Solubility

10 mM in DMSO

Smiles

CC(C)C1=NC(C2=CC=C(NC(NC3=CC=CC(C(F)(F)F)=C3)=O)C4=C2C=CC=C4)=C5N1C=CN=C5NC

Molecular Formula

C28H25F3N6O

Molecular Weight

518.53

References & Citations

[1]Wang L, et al. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012 Dec;8 (12) :982-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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