NIBR-17
NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].
Product Specifications
CAS Number
[944396-88-7]
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nibr-17.html
Solubility
10 mM in DMSO
Smiles
NC1=NC=C(C2=NC(N3CCOCC3)=NC(NC4=CC=C(OC)N=C4)=C2)C=N1
Molecular Formula
C18H20N8O2
Molecular Weight
380.40
References & Citations
[1]Burger MT, et al. Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors. ACS Med Chem Lett. 2010 Oct 13;2 (1) :34-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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