NIBR-17

NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].

Product Specifications

CAS Number

[944396-88-7]

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nibr-17.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=C(C2=NC(N3CCOCC3)=NC(NC4=CC=C(OC)N=C4)=C2)C=N1

Molecular Formula

C18H20N8O2

Molecular Weight

380.40

References & Citations

[1]Burger MT, et al. Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors. ACS Med Chem Lett. 2010 Oct 13;2 (1) :34-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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