ASK1-IN-5
ASK1-IN-5 (S-99) is an inhibitor of apoptosis signal-regulated kinase 1 (ASK1) and is useful in the study of autoimmune and neurodegenerative diseases[1].
Product Specifications
CAS Number
[1124381-69-6]
UNSPSC
12352005
Hazard Statement
H317
Target
Apoptosis; ASK1; MAP3K
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ask1-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CN=C1)NC2=NN3C(NC(C)C)=CC(C(F)(F)F)=CC3=N2
Molecular Formula
C16H15F3N6O
Molecular Weight
364.33
Precautions
H317
References & Citations
[1]Dominique Swinnen, et al.Triazolopyridine compounds and their use as ask inhibitors.WO2009027283A1
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP3K5/ASK1
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