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Berberine-d6 (chloride)

Product Specifications

UNSPSC Description

Berberine-d6 (chloride) is the deuterium labeled Berberine chloride. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].

Target Antigen

Antibiotic; Autophagy; Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species; Topoisomerase

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])OC1=C(OC([2H])([2H])[2H])C2=C[N+]3=C(C4=CC5=C(C=C4CC3)OCO5)C=C2C=C1.[Cl-]

Molecular Weight

377.85

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Curated Selection

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