Fosnetupitant
Fosnetupitant (Pronetupitant) a methylene phosphate proagent of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pKi of 9.5 for human NK1 receptor[1].
Product Specifications
CAS Number
[1703748-89-3]
Product Name Alternative
Pronetupitant
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/fosnetupitant.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=P(OC[N+]1(C)CCN(C2=NC=C(N(C)C(C(C)(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)=O)C(C4=CC=CC=C4C)=C2)CC1)([O-])O
Molecular Formula
C31H35F6N4O5P
Molecular Weight
688.60
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Ruzza C, et al. In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant. Peptides. 2015 Jul;69:26-32.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
038845-AP 200 µL
NDOR1, ID (NDOR1, NR1, NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase, Novel reductase 1) (AP) discontinued
Ask
View Details 
GTR15369893 1 Vial
Lentiviral human NEXN sgRNA gene knockout kit - Lentiviral human NEXN sgRNA gene knockout kit (plasmid)
Ask
View Details