Bictegravir-15N, d2
Bictegravir-15N, d2 (GS-9883-15N, d2) is the 15N and deuterium labeled Bictegravir (HY-17605) [1]. Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM[2].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
96.09
Solubility
DMSO : 83.3 mg/mL (ultrasonic; warming)
Smiles
O=C1N([C@](CC2)([H])C[C@]2([H])O3)[C@@]3([H])CN(C=C(C([15NH]C([2H])([2H])C(C(F)=CC(F)=C4)=C4F)=O)C5=O)C1=C5O
Molecular Formula
C21H16D2F3N2 15NO5
Molecular Weight
452.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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