Dalbavancin
Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively[1][2].
Product Specifications
CAS Number
171500-79-1
Product Name Alternative
MDL-63397; BI-397
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dalbavancin-1.html
Purity
99.65
Solubility
10 mM in DMSO
Smiles
O[C@@H]([C@@H](O)[C@@H]1O)[C@H](O[C@@H]1CO)OC2=C(C3=CC([C@@](C4=O)([H])NC([C@@](NC([C@](NC([C@@](NC5=O)([H])C6)=O)([H])C(C=C7OC(C=C8[C@H]5NC)=C(C=C8)O)=C(C(O)=C7)Cl)=O)([H])C9=CC%10=C(O[C@H](O[C@H](C(O)=O)[C@@H](O)[C@@H]%11O)[C@@H]%11NC(CCCCCCCCC(C)C)=O)C(OC%12=CC=C6C=C%12)=C9)=O)=CC=C3O)C([C@@](NC([C@](N4)([H])[C@@H](C%13=CC=C(O%10)C(Cl)=C%13)O)=O)([H])C(NCCCN(C)C)=O)=CC(O)=C2
Molecular Formula
C88H100Cl2N10O28
Molecular Weight
1816.69
Precautions
H315, H319, H335
References & Citations
[1]Heine HS, et al. Activity of dalbavancin against Bacillus anthracis in vitro and in a mouse inhalation anthrax model. Antimicrob Agents Chemother. 2010 Mar;54 (3) :991-6.|[2]Bennett JW, et al. Dalbavancin in the treatment of complicated skin and soft-tissue infections: a review. Ther Clin Risk Manag. 2008 Feb;4 (1) :31-40.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Glycopeptide
Citation 01
Cell Res. 2021 Jan;31 (1) :17-24.|Enferm Infec Micr Cl. 30 July 2022.|Eur J Orthop Surg Traumatol. 2023 Dec;33 (8) :3655-3659.|Sci Rep. 2022 Sep 26;12 (1) :16001.|Sci Rep. 2025 May 2;15 (1) :15346.|Antivir Res. 2020 Jun;178:104786.|Cell Res. 2021 Jan;31 (1) :17-24.|The Journal of Antibiotics . 2019 Feb;72 (2) :114-117.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
