Carteolol
Carteolol is a non-selective β-adrenoceptor antagonist. Carteolol induces apoptosis via a caspase activated and mitochondrial-dependent pathway. Carteolol can be used for glaucoma research[1].
Product Specifications
CAS Number
[51781-06-7]
Product Name Alternative
OPC-1085
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor; Bcl-2 Family; Caspase
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/carteolol.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=C(C(OCC(O)CNC(C)(C)C)=CC=C2)CC1
Molecular Formula
C16H24N2O3
Molecular Weight
292.37
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Su W, et, al. Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms. Front Pharmacol. 2020 Mar 6;11:202.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
ACS Omega. 2022 Aug 8;7 (32) :27950-27958.|J Pharm Biomed Anal. 2021 Feb 20:195:113870.
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