Tranylcypromine-d5 (hydrochloride)

Tranylcypromine-d5 (hydrochloride) is a deuterium labeled (rel) -Tranylcypromine hydrochloride. Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].

Product Specifications

CAS Number

[107077-98-5]

Product Name Alternative

SKF 385-d5 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Histone Demethylase; Monoamine Oxidase

Type

Isotope-Labeled Compounds

Related Pathways

Epigenetics; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

N[C@H]1[C@H](C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C1.[H]Cl

Molecular Formula

C9H7D5ClN

Molecular Weight

174.68

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ (1-42) -induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263.|[2]Sun Q, et al. Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17.