(1S,2R)-Tranylcypromine (hydrochloride)
Product Specifications
UNSPSC Description
(1S,2R)-Tranylcypromine ((1S,2R)-SKF 385) hydrochloride is a potent antidepressant agent. (1S,2R)-Tranylcypromine hydrochloride can inhibits MAO and LSD1[1][2].
Target Antigen
Histone Demethylase; Monoamine Oxidase
Type
Reference compound
Related Pathways
Epigenetics;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/1s-2r-tranylcypromine-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
N[C@H]1C[C@@H]1C2=CC=CC=C2.[H]Cl
Molecular Weight
169.65
References & Citations
[1]TetsuyaEzawa, et al. Amidation of carboxylic acids via the mixed carbonic carboxylic anhydrides and its application to synthesis of antidepressant (1S,2R)-tranylcypromine. Tetrahedron: Asymmetry. 15 December 2017;28(12):1690-1699.|[2]Valente S, et al. Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies. ACS Med Chem Lett. 2014 Dec 8;6(2):173-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-17447B/1S-2R-Tranylcypromine-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17447B/
Clinical Information
Launched
CAS Number
4548-34-9
Curated Selection
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