Acyclovir monophosphate
Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity[1][2].
Product Specifications
CAS Number
[66341-16-0]
UNSPSC
12352005
Target
Antibiotic; HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/acyclovir-monophosphate.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(NC2=C1N=CN2COCCOP(O)(O)=O)N
Molecular Formula
C8H12N5O6P
Molecular Weight
305.18
References & Citations
[1]Yao J, et al. Turning an antiviral into an anticancer drug: nanoparticle delivery of acyclovir monophosphate. J Control Release. 2013 Sep 28;170 (3) :414-20.|[2]Elion GB, et al. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73 (1A) :7-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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