Agomelatine-d3
Agomelatine-d3 is the deuterium labeled Agomelatine. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively[1]. Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively[2].
Product Specifications
CAS Number
[1079389-38-0]
Product Name Alternative
S-20098-d3
UNSPSC
12352005
Target
5-HT Receptor; Endogenous Metabolite; Melatonin Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Purity
98.0
Solubility
10 mM in DMSO|DMSO : ≥ 100mg/mL
Smiles
[2H]C([2H])([2H])C(NCCC1=CC=CC2=C1C=C(OC)C=C2)=O
Molecular Formula
C15H14D3NO2
Molecular Weight
246.32
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17038S2/Agomelatine-d3-SDS-MedChemExpress.pdf
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; MT1; MT2
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