Caspofungin

Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β- (l,3) -D-glucan[1][2].

Product Specifications

CAS Number

[162808-62-0]

Product Name Alternative

MK-0991; L-743872

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Antibiotic; Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/caspofungin.html

Purity

99.74

Solubility

10 mM in DMSO

Smiles

O=C([C@](NC([C@](NC([C@@](C[C@H]1O)([H])N(C1)C2=O)=O)([H])[C@H](O)[C@H](C(C=C3)=CC=C3O)O)=O)([H])[C@H](O)CCN)N(CC[C@@H]4O)[C@]4([H])C(N[C@@H]([C@@H](C[C@@H](C(N[C@@]2([H])[C@H](O)C)=O)NC(CCCCCCCC[C@@H](C)C[C@@H](C)CC)=O)O)NCCN)=O

Molecular Formula

C52H88N10O15

Molecular Weight

1093.31

Precautions

H302, H312, H332

References & Citations

[1]Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55 (7) :3491-7. |[2]Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51 (11) :5796-803.