Caspofungin
Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β- (l,3) -D-glucan[1][2].
Product Specifications
CAS Number
162808-62-0
Product Name Alternative
MK-0991; L-743872
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Antibiotic; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/caspofungin.html
Purity
99.74
Solubility
10 mM in DMSO
Smiles
O=C([C@](NC([C@](NC([C@@](C[C@H]1O)([H])N(C1)C2=O)=O)([H])[C@H](O)[C@H](C(C=C3)=CC=C3O)O)=O)([H])[C@H](O)CCN)N(CC[C@@H]4O)[C@]4([H])C(N[C@@H]([C@@H](C[C@@H](C(N[C@@]2([H])[C@H](O)C)=O)NC(CCCCCCCC[C@@H](C)C[C@@H](C)CC)=O)O)NCCN)=O
Molecular Formula
C52H88N10O15
Molecular Weight
1093.31
Precautions
H302, H312, H332
References & Citations
[1]Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55 (7) :3491-7. |[2]Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51 (11) :5796-803.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
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