Fluralaner-13C2,15N, d3
Fluralaner-13C2,15N, d3 is the deuterium, 13C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
Product Specifications
Product Name Alternative
A1443-13C2,15N, d3; AH252723-13C2,15N, d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
98.35
Solubility
10 mM in DMSO
Smiles
O=C([15NH][13CH2][13C](NCC(F)(F)F)=O)C1=CC=C(C2=NOC(C(F)(F)F)(C3=C([2H])C(Cl)=C([2H])C(Cl)=C3[2H])C2)C=C1C
Molecular Formula
C20 13C2H14D3Cl2F6N2 15NO3
Molecular Weight
562.28
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[2]Walther FM, et al. Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1 (-/-) Collies after oral administration. Parasit Vectors. 2014 Mar 6;7:86.|[3]Williams H, et al. Fluralaner, a novel isoxazoline, prevents flea (Ctenocephalides felis) reproduction in vitro and in asimulated home environment. Parasit Vectors. 2014 Jun 19;7:275.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
Mite
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