What is the catalog number for Ulipristal acetate-d6?

The catalog number for Ulipristal acetate-d6 is HY-16508S.

What sizes are available for Ulipristal acetate-d6?

Ulipristal acetate-d6 is available in the following size(s): 5 mg.

Is Ulipristal acetate-d6 in stock?

Ulipristal acetate-d6 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ulipristal acetate-d6?

Ulipristal acetate-d6 is manufactured by QuantiMol.

What is the estimated delivery time for Ulipristal acetate-d6?

Estimated delivery time for Ulipristal acetate-d6 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ulipristal acetate-d6?

The safety data sheet for Ulipristal acetate-d6 is available here: http://file.medchemexpress.com/batch_PDF/HY-16508S/.

Ulipristal acetate-d6

Ulipristal acetate-d6 is deuterium labeled Ulipristal acetate. Ulipristal acetate (CDB-2914) is an orally active, selective progesterone receptor modulator (SPRM) . Ulipristal acetate stimulates the autophagic response selectively in leiomyoma cells. Ulipristal acetate has the potential for benign gynecological conditions treatment, such as uterine myoma[1][2].

Product Specifications

CAS Number

1621894-64-1

Product Name Alternative

CDB-2914-d6

UNSPSC

12352005

Hazard Statement

H302+H312+H332-H315-H319

Target

Autophagy; Isotope-Labeled Compounds; Progesterone Receptor

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; Others; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Cancer

Solubility

10 mM in DMSO

Smiles

O=C1CCC2=C3[C@@]([H])(CCC2=C1)[C@@]([H])([C@@]4(C[C@@H]3C5=CC=C(C=C5)N(C([2H])([2H])[2H])C([2H])([2H])[2H])C)CC[C@@]4(C(C)=O)OC(C)=O

Molecular Formula

C30H31D6NO4

Molecular Weight

481.66

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2] Attardi BJ, et al. In vitro antiprogestational/antiglucocorticoid activity and progestin and glucocorticoid receptor binding of the putative metabolites and synthetic derivatives of CDB-2914, CDB-4124, and mifepristone. J Steroid Biochem Mol Biol.|[3]Ciarmela P, et al. Ulipristal acetate modulates the expression and functions of activin a in leiomyoma cells. Reprod Sci. 2014 Sep;21 (9) :1120-5.|[4]Del Bello B, et al. Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study. Fertil Steril. 2019 Dec;112 (6) :1150-1159.|[5]Hild SA, et al. CDB-2914: anti-progestational/anti-glucocorticoid profile and post-coital anti-fertility activity in rats and rabbits. Hum Reprod. 2000 Apr;15 (4) :822-9.|[6]Jadav SP, et al. Ulipristal acetate, a progesterone receptor modulator for emergency contraception. J Pharmacol Pharmacother. 2012 Apr;3 (2) :109-11.|[7]Pohl O, et al. A 39-week oral toxicity study of ulipristal acetate in cynomolgus monkeys. Regul Toxicol Pharmacol. 2013 Jun;66 (1) :6-12.|[8]Pohl O, et al. Carcinogenicity and chronic rodent toxicity of the selective progesterone receptor modulator ulipristal acetate. Curr Drug Saf. 2013 Apr;8 (2) :77-97.