Terodiline (hydrochloride)
Terodiline hydrochloride is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline hydrochloride also is a Ca2+ blocker. Terodiline hydrochloride acts as a treatment for urinary frequency and urge incontinence[1].
Product Specifications
CAS Number
7082-21-5
UNSPSC
12352005
Hazard Statement
H302, H319, H400
Target
Calcium Channel; mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/terodiline-hydrochloride.html
Purity
99.78
Solubility
DMSO : 40 mg/mL (ultrasonic; warming)
Smiles
CC(NC(C)(C)C)CC(C1=CC=CC=C1)C2=CC=CC=C2.[H]Cl
Molecular Formula
C20H28ClN
Molecular Weight
317.90
Precautions
H302, H319, H400
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR1; mAChR3
Frequently Asked Questions
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