Solenopsin
Solenopsin ((-) -Solenopsin A) is an ATP-competitive AKT inhibitor with IC50 value of 10 μM[1].
Product Specifications
CAS Number
[137038-57-4]
Product Name Alternative
(-) -Solenopsin A
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/SOLENOPSIN.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCC[C@@H]1CCC[C@@H](C)N1
Molecular Formula
C17H35N
Molecular Weight
253.47
References & Citations
[1]Arbiser JL, et al. Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis. Blood. 2007 Jan 15;109 (2) :560-5. Epub 2006 Sep 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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