Nedocromil sodium

Nedocromil sodium suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2) .

Product Specifications

CAS Number

[69049-74-7]

Product Name Alternative

FPL 59002KP; Nedocromil disodium salt

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Histamine Receptor; Leukotriene Receptor; Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/NEDOCROMIL_SODIUM.html

Solubility

DMSO : 5.2 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(C2=CC3=C(N(CC)C(C([O-])=O)=CC3=O)C(CCC)=C2O1)=O)[O-].[Na+].[Na+]

Molecular Formula

C19H15NNa2O7

Molecular Weight

415.30

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wells E, et al. Characterization of primate bronchoalveolar mast cells. II. Inhibition of histamine, LTC4, and PGD2 release from primate bronchoalveolar mast cells and a comparison with rat peritoneal mastcells. J Immunol. 1986 Dec 15;137 (12) :3941-5.|[2]Myocardial remodeling in diabetic cardiomyopathy associated with cardiac mast cell activation. Huang ZG, et al. PLoS One. 2013;8 (3) :e60827.