SARS-CoV-2 Mpro-IN-14
SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19[1].
Product Specifications
CAS Number
2679814-93-6
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-mpro-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(N(C)C=C1C(C=C2C3=CC(OCC4=C(Cl)C=CC=C4)=C(F)C(Cl)=C3)=CN(C5=CC=CN=C5)C2=O)=O
Molecular Formula
C28H19Cl2FN4O4
Molecular Weight
565.38
References & Citations
[1]Zhang CH, et al. Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. ACS Med Chem Lett. 2021 Jul 14;12 (8) :1325-1332.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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