Tubulin inhibitor 40
Product Specifications
UNSPSC Description
Tubulin inhibitor 40 (compound 45) is a tubulin inhibitor with IC50 of 1.2 μM. Tubulin inhibitor 40 shows selective cytotoxicity towards cancer cells. Tubulin inhibitor 40 processes antitumor activity [1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-40.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C(OC)=CC(C2=CON=C2C3=CC=C(C(N)=C3)OC)=C1)OC
Molecular Weight
356.37
References & Citations
[1]Georgy L et al., 3,4-Diarylisoxazoles─Analogues of Combretastatin A-4: Design, Synthesis, and Biological Evaluation In Vitro and In Vivo. ACS Pharmacology & Translational Science Article ASAP, January 16, 2024
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163195/Tubulin-inhibitor-40-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163195/
Clinical Information
No Development Reported
Curated Selection
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