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Tubulin inhibitor 40

Selected Variant

HY-163195

Size: 1 Each

Tubulin inhibitor 40 (compound 45) is a tubulin inhibitor with IC50 of 1.2 μM. Tubulin inhibitor 40 shows selective cytotoxicity towards cancer cells. Tubulin inhibitor 40 processes antitumor activity [1].

Product Specifications

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-40.html

Solubility

10 mM in DMSO

Smiles

COC1=C(C(OC)=CC(C2=CON=C2C3=CC=C(C(N)=C3)OC)=C1)OC

Molecular Formula

C19H20N2O5

Molecular Weight

356.37

References & Citations

[1]Georgy L et al., 3,4-Diarylisoxazoles─Analogues of Combretastatin A-4: Design, Synthesis, and Biological Evaluation In Vitro and In Vivo. ACS Pharmacology & Translational Science Article ASAP, January 16, 2024

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Price

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