DCLK1-IN-4
DCLK1-IN-4 (compound D2) is a potent and selective doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 70 nM. DCLK1-IN-4 can be used for the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dclk1-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC(NC1=CC=C(NC2=NC=C(C(N(C)C3=CC=CC=C34)=N2)N(C)C4=O)C(OC)=C1)=O
Molecular Formula
C24H24N6O5
Molecular Weight
476.48
References & Citations
[1]Pan P, et al. Design and synthesis of doublecortin-like kinase 1 inhibitors and their bioactivity evaluation. J Enzyme Inhib Med Chem. 2024 Dec;39 (1) :2287990.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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