DCLK1-IN-3

DCLK1-IN-3 is a potent and selective doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 47 nM. DCLK1-IN-3 can be used for the research of cancer[1].

Product Specifications

UNSPSC

12352005

Target

Ser/Thr Protease

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dclk1-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC(NC1=CC=C(NC2=NC=C(C(N(C)C3=CC=CC=C34)=N2)N(C)C4=O)C(OC)=C1)=O

Molecular Formula

C23H22N6O5

Molecular Weight

462.46

References & Citations

[1]Pan P, et al. Design and synthesis of doublecortin-like kinase 1 inhibitors and their bioactivity evaluation. J Enzyme Inhib Med Chem. 2024 Dec;39 (1) :2287990.