VH 032 amide-alkylC5-azide
VH 032 amide-alkylC5-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand[1].
Product Specifications
CAS Number
2821804-11-7
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/vh-032-amide-alkylc5-azide.html
Purity
98.32
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
[N-]=[N+]=NCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O
Molecular Formula
C28H39N7O4S
Molecular Weight
569.72
References & Citations
[1]Chengyuan Liang, et al. Protacs based on VHL ligand targeting coronavirus 3CL protease and preparation method and application thereof. US11518759B1.2022-12-06.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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