PHD-IN-3
PHD-IN-3 (Compound 15) is an orally active PHD inhibitor. PHD-IN-3 can be used in the study of anemia associated with chronic kidney disease[1].
Product Specifications
CAS Number
2924181-77-9
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/phd-in-3.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1CCN(C1)C2=NC3=C(C(O)=C(N=C3)C(NCC4=CN=C(C=C4)C#N)=O)C=C2
Molecular Formula
C20H18N6O3
Molecular Weight
390.40
References & Citations
[1]Xu J, et al. Discovery of Novel and Potent Prolyl Hydroxylase Domain-Containing Protein (PHD) Inhibitors for The Treatment of Anemia. J Med Chem. 2024 Jan 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1028947-01 0.02 mg (E-Coli)
Recombinant Salmonella paratyphi B Co-chaperone protein hscB (hscB)
Sign In for Pricing
View Details MBS1028947-02 0.1 mg (E-Coli)
Recombinant Salmonella paratyphi B Co-chaperone protein hscB (hscB)
Sign In for Pricing
View Details MBS1028947-03 0.02 mg (Yeast)
Recombinant Salmonella paratyphi B Co-chaperone protein hscB (hscB)
Sign In for Pricing
View Details MBS1028947-04 0.1 mg (Yeast)
Recombinant Salmonella paratyphi B Co-chaperone protein hscB (hscB)
Sign In for Pricing
View Details MBS1028947-05 0.02 mg (Baculovirus)
Recombinant Salmonella paratyphi B Co-chaperone protein hscB (hscB)
Sign In for Pricing
View Details MBS1028947-06 0.02 mg (Mammalian-Cell)
Recombinant Salmonella paratyphi B Co-chaperone protein hscB (hscB)
Sign In for Pricing
View Details