TME-HYM (PH Probe)

TME-HYM (PH Probe) is a novel fluorescent probe based on acidic tumor microenvironment (TME) activation and organic anion transporting polypeptide (OATPs, overexpressed on cancer cells), and can be selective uptaken. TME-HYM (PH Probe) can selectively lit up cancer cells and tumor tissues, offering dual tumor selectivity for precise visualization of tumor mass[1].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tme-hym-ph-probe.html

Solubility

10 mM in DMSO

Smiles

CC1=NC(/C=C/C2=[N+](C3=C(C2(C)C)C4=C(C=C(C=C4)I)C=C3)C)=CC5=C1N(C6=CC=CC=C65)CCN7CCOCC7.[I-]

Molecular Formula

C35H36I2N4O

Molecular Weight

782.50

References & Citations

[1]Xu Z, et al. Dual Tumor-Selective β-Carboline-Based Fluorescent Probe for High-Contrast/Rapid Diagnosis of Clinical Tumor Tissues. Mol Pharm. 2024 Jan 1;21 (1) :152-163.