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Antibacterial agent 172

Antibacterial agent 172 (Compound 6a) is a Clostridioides difficile (Cd) SpoVD inhibitor (IC50=89 nM) that effectively inhibits sporulation of Clostridioides difficile. Antibacterial agent 172 can be used in the study of bacterial infections[1].

Product Specifications

CAS Number

3023114-93-1

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-172.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@@](NC(CN4N=NC(C5=CC=CC=C5)=C4)=O)(OC)C1=O)O

Molecular Formula

C21H21N9O5S2

Molecular Weight

543.58

References & Citations

[1]Cun WY, et al. Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile. J Med Chem. 2024 Jan 11;67 (1) :450-466.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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