DAT-IN-1
DAT-IN-1 (Coumpound 12b) is an atypical DAT inhibitor with a Ki of 8.37 nM. DAT-IN-1 can be used in the study of psychostimulant use disorder (PSUD) [1].
Product Specifications
UNSPSC
12352005
Target
Dopamine Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dat-in-1.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C(C2=CC=C(C=C2)F)S(CCN3CCCN(CC3)CC(CC4=CC=CC=C4)O)=O)C=C1
Molecular Formula
C29H34F2N2O2S
Molecular Weight
512.65
References & Citations
[1]Okorom AV, et al. Modifications to 1- (4- (2-Bis (4-fluorophenyl) methyl) sulfinyl) alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile. J Med Chem. 2023 Dec 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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