Telomerase-IN-6

Telomerase-IN-6 (6f) is a telomerase inhibitor with antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Telomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/telomerase-in-6.html

Solubility

10 mM in DMSO

Smiles

OC1=NC(SCC(NC2=CC=C(C=C2)Cl)=O)=NC(C3=CC=CN=C3)=C1C#N

Molecular Formula

C18H12ClN5O2S

Molecular Weight

397.84

References & Citations

[1]Ahmed A Al-Karmalawy, et al. Lead Optimization of BIBR1591 To Improve Its Telomerase Inhibitory Activity: Design and Synthesis of Novel Four Chemical Series with In Silico, In Vitro, and In Vivo Preclinical Assessments. J Med Chem. 2024 Jan 11;67 (1) :492-512.