Autophagy/REV-ERB-IN-1
Autophagy/REV-ERB-IN-1 (compound 24) is a dual inhibitor of autophagy and REV-ERB. Autophagy/REV-ERB-IN-1 has anti-tumor activity with a CC50 value of 2.3 μM on BTB-474 cells.
Product Specifications
UNSPSC
12352005
Target
Autophagy; REV-ERB
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/autophagy-rev-erb-in-1.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C2(NCC3=CC=C(F)C(CC4CCNCC4)=C3)CCCC2)C=C1
Molecular Formula
C24H30F2N2
Molecular Weight
384.51
References & Citations
[1]Martina Palomba, et al. Identification of a Dual Autophagy and REV-ERB Inhibitor with in Vivo Anticancer Efficacy. J Med Chem. 2024, 67, 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6408065-01 0.1 mL
BAD (Bcl2 Antagonist of Cell Death, BBC2, BCL2L8) (MaxLight 405)
Sign In for Pricing
View Details 
MBS6408065-02 5x 0.1 mL
BAD (Bcl2 Antagonist of Cell Death, BBC2, BCL2L8) (MaxLight 405)
Sign In for Pricing
View Details RC214908L3V 200 µL
NIPAL4 (NM_001099287) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details C7904-73C 100 µg
COX 1 (PTGS1, COX1, COX3, PHS1, PCOX1, PGHS1, PTGHS, PGG/HS, PGHS-1, Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase), Prostaglandin G/H synthase and cyclooxygenase)
Sign In for Pricing
View Details 
RG210049 10 µg
Cytokeratin 18 (KRT18) (NM_199187) Human Tagged ORF Clone
Sign In for Pricing
View Details