Autophagy/REV-ERB-IN-1
Autophagy/REV-ERB-IN-1 (compound 24) is a dual inhibitor of autophagy and REV-ERB. Autophagy/REV-ERB-IN-1 has anti-tumor activity with a CC50 value of 2.3 μM on BTB-474 cells.
Product Specifications
UNSPSC
12352005
Target
Autophagy; REV-ERB
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/autophagy-rev-erb-in-1.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C2(NCC3=CC=C(F)C(CC4CCNCC4)=C3)CCCC2)C=C1
Molecular Formula
C24H30F2N2
Molecular Weight
384.51
References & Citations
[1]Martina Palomba, et al. Identification of a Dual Autophagy and REV-ERB Inhibitor with in Vivo Anticancer Efficacy. J Med Chem. 2024, 67, 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15083303 1 Vial
Lentiviral human RUSC1 shRNA (UAS) - Lentiviral human RUSC1 shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details MBS7148634 Inquire
Rabbit anti-Escherichia coli (strain K12) TATC Polyclonal Antibody
Sign In for Pricing
View Details 
MBS6220154-01 0.1 mL
Neisseria gonorrhoeae (Gonorrhea) (MaxLight 650)
Sign In for Pricing
View Details MBS6220154-02 5x 0.1 mL
Neisseria gonorrhoeae (Gonorrhea) (MaxLight 650)
Sign In for Pricing
View Details TL508395V 500 µL Each
H4c1 Mouse shRNA Lentiviral Particle (Locus ID 326619)
Sign In for Pricing
View Details 46678114 3x 1.0 µg
Thtpa sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details