Anticancer agent 180

Anticancer agent 180 (compound 4) is a secondary metabolite induced by co-culture of fungi and actinomycetes, the later one can produce HDAC inhibitors Trichostatins. Anticancer agent 180 has potential anti-tumor activity and can inhibit the migration of MDA-MB-231 breast cancer cells[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-180.html

Solubility

10 mM in DMSO

Smiles

OC(C(C1=CC=C(C=C1)O)=CN(C)C2=O)=C2[C@@]3([H])O[C@](CCC(CC(CC)C)C)([H])CCC3

Molecular Formula

C26H37NO4

Molecular Weight

427.58

References & Citations

[1]Hwang GJ, et al. Induction of Fungal Secondary Metabolites by Co-Culture with Actinomycete Producing HDAC Inhibitor Trichostatins. J Microbiol Biotechnol. 2023 Nov 28;33 (11) :1437-1447.