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Antibacterial agent 169

Antibacterial agent 169 (Compound 28) is a pyrrolamide-type GyrB/ParE inhibitor with antibacterial activity. Antibacterial agent 169 has an inhibitory effect on Gyrase and Topo IV of Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L respectively[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-169.html

Solubility

10 mM in DMSO

Smiles

CO[C@H]1CN(C2=CC=C(N=N2)C(C)(O)C)CC[C@H]1NC(C3=C(C(Cl)=C(N3)C)Cl)=O

Molecular Formula

C19H25Cl2N5O3

Molecular Weight

442.34

References & Citations

[1]Zhao X, et al. Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection. Acta Pharm Sin B. 2023 Dec;13 (12) :4945-4962.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-163104/Antibacterial-agent-169-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-163104/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[2879255-03-3]

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