Antibacterial agent 169
Antibacterial agent 169 (Compound 28) is a pyrrolamide-type GyrB/ParE inhibitor with antibacterial activity. Antibacterial agent 169 has an inhibitory effect on Gyrase and Topo IV of Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L respectively[1].
Product Specifications
CAS Number
2879255-03-3
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-169.html
Solubility
10 mM in DMSO
Smiles
CO[C@H]1CN(C2=CC=C(N=N2)C(C)(O)C)CC[C@H]1NC(C3=C(C(Cl)=C(N3)C)Cl)=O
Molecular Formula
C19H25Cl2N5O3
Molecular Weight
442.34
References & Citations
[1]Zhao X, et al. Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection. Acta Pharm Sin B. 2023 Dec;13 (12) :4945-4962.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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