GB1490
Product Specifications
UNSPSC Description
GB1490 is an orally active galectin inhibitor with Kd values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively[1].
Target Antigen
Galectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gb1490.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](N2C=C(C3=NC=CS3)N=N2)[C@H]([C@H](O[C@@H]1SC4=CC(Cl)=C(C(Cl)=C4)F)CO)O
Molecular Weight
493.36
References & Citations
[1]Fredrik R Zetterberg, et al. Discovery of Selective and Orally Available Galectin-1 Inhibitors. J Med Chem. 2023 Dec 7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163082/GB1490-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163082/
Clinical Information
No Development Reported
CAS Number
2172866-22-5
Curated Selection
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