V023-9340

V023-9340 is a potent FXR inhibitor with IC50 of 4.27 μM that can be used in NASH (nonalcoholic steatohepatitis) research[1].

Product Specifications

CAS Number

[1048304-96-6]

UNSPSC

12352005

Target

FXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/v023-9340.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC1=CC=C2OCOC2=C1)CC3=CC=C(C=C3)N(C(C4CCCC4)=O)CC5=CC=CC(C)=C5

Molecular Formula

C30H32N2O4

Molecular Weight

484.59

References & Citations

[1]Cong Chen, et al. Discovery of 4-aminophenylacetamide derivatives as intestine-specific farnesoid X receptor antagonists for the potential treatment of nonalcoholic steatohepatitis. Eur J Med Chem. 2023 Nov 27:264:115992.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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