Antitubercular agent-43
Antitubercular agent-43 (compound A11) is an orally active and potent antitubercular agent. Antitubercular agent-43 shows highly metabolic stability against human and mouse cytochrome P450 enzymes. Antitubercular agent-43 exhibits bactericidal efficacy in acute TB infection mouse model[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitubercular-agent-43.html
Solubility
10 mM in DMSO
Smiles
CN(C1=NC(C2=CC(C(F)(F)F)=CC([N+]([O-])=O)=C2S1)=O)CC#CC3=CSC=N3
Molecular Formula
C16H9F3N4O3S2
Molecular Weight
426.39
References & Citations
[1]Wu X, et al. Benzothiozinone derivatives with anti-tubercular Activity-Further side chain investigation. Eur J Med Chem. 2023 Nov 25;264:115976.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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