FLT3-IN-24
FLT3-IN-24 (compound 24) is a potent and selective inhibitor of FLT3 kinase with an IC50 of 7.94 nM. FLT3-IN-24 has cell antiproliferative effects[1].
Product Specifications
UNSPSC
12352005
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-in-24.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(C1=CC=C(C=C1)NC2=CC=CC(C3=CN=C4C=C(C=CN34)C5=CN(C)N=C5)=N2)=O
Molecular Formula
C23H20N6O2S
Molecular Weight
444.51
References & Citations
[1]Wang X, et al.An imidazo [1, 2-a] pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L[J]. European Journal of Medicinal Chemistry, 2023: 115977.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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