SARS-CoV-2-IN-71

SARS-CoV-2-IN-71 (compound 8h) is a potent inhibitor of SARS-CoV-2. SARS-CoV-2-IN-71 inhibits coronavirus replication at multiple stages. SARS-CoV-2-IN-71 displays anti-coronaviral effect by simultaneously acting on 3CLpro and TMPRSS2[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-in-71.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(C(C(F)(F)F)=C1)CN2CC(C2)N(C)C)C(C=C3[N+]([O-])=O)=CC=C3OCCC(F)(F)F

Molecular Formula

C23H24F6N4O4

Molecular Weight

534.45

References & Citations

[1]Li J, et al. Design, synthesis and biological evaluation of biaryl amide derivatives against SARS-CoV-2 with dual-target mechanism. Eur J Med Chem. 2023 Nov 25;264:115978.