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α-Glucosidase-IN-44

α-Glucosidase-IN-44 (compound IT4) is an inhibitor of α-glucosidase with IC50 value of 2.35 μM. α-Glucosidase-IN-44 has an oral activity. α-Glucosidase-IN-44 suppresses fasting blood glucose levels in diabetic mice[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-44.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCC1=CNC2=C1C=CC=C2)CN3C(S/C(C3=O)=C\C4=CC=C(C)C=C4)=O

Molecular Formula

C23H21N3O3S

Molecular Weight

419.50

References & Citations

[1]Chunmei Hu, et al. Synthesis and biological evaluation of indole derivatives containing thiazolidine-2,4-dione as α-glucosidase inhibitors with antidiabetic activity. Eur J Med Chem. 2023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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