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Antimalarial agent 34

Antimalarial agent 34 is a modest PfARK1/3 inhibitor and shows potent antiplasmodial activity (EC50 = 0.16 μM) [1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antimalarial-agent-34.html

Solubility

10 mM in DMSO

Smiles

CS(=O)(NC1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCOCC4)C(OC)=C3)=NC=C2Cl)=O

Molecular Formula

C22H25ClN6O4S

Molecular Weight

504.99

References & Citations

[1]Han Wee Ong, et al. Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB. ACS Med Chem Lett. 2023 Nov 27;14 (12) :1774-1784.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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