HSGN-218

HSGN-218 is an antibacterial agent with low Caco-2 permeability. HSGN-218 efficiently inhibits the growth of different C. difficile species with MIC values ranging from 0.007 μM to 0.07 μM.[1]

Product Specifications

CAS Number

[2519410-44-5]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hsgn-218.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NN=C(C2=CC(Cl)=CC(Cl)=C2)O1)C3=CC=C(SC(F)(F)F)C=C3

Molecular Formula

C16H8Cl2F3N3O2S

Molecular Weight

434.22

References & Citations

[1]Naclerio GA, et al. Ultrapotent Inhibitor of Clostridioides difficile Growth, Which Suppresses Recurrence In Vivo. J Med Chem. 2020 Oct 22;63 (20) :11934-11944.