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PD-1/PD-L1-IN-36

PD-1/PD-L1-IN-36 (Compound 2k) is a PD-1/PD-L1 complex inhibitor (IC50: 15 nM) . PD-1/PD-L1-IN-36 can be used for research of cancer immunotherapy[1].

Product Specifications

CAS Number

2714327-65-6

UNSPSC

12352005

Target

PD-1/PD-L1

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pd-1-pd-l1-in-36.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(CC2=CC=C(OCC3=C(Br)C(C4=CC=CC=C4)=CC=C3)C(Br)=C2)CCCC1)O

Molecular Formula

C26H25Br2NO3

Molecular Weight

559.29

References & Citations

[1]Konieczny M, et al. Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint. J Med Chem. 2020 Oct 8;63 (19) :11271-11285.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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